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Vonderheide Laboratory

Summary:

The Vonderheide laboratory combines efforts in both basic research and clinical investigation to advance the understanding of tumor immunology and to develop novel immunotherapies for cancer. The chief hypothesis is that successful approaches in tumor immunotherapy will need to (a) optimize target antigens with regard to clinical applicability and risk of antigen loss, (b) repair host immuno-incompetence in antigen presentation and T cell function, and (c) circumvent immuno-suppressive factors of the tumor and tumor microenvironment.

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Organisms and Viruses

  • Kras G12D ( Mus musculus )

    These mice are commerically available. Cryo-preservation planned for near future.

  • p53R172H ( Mus musculus )

    These mice are commerically available. Cryo-preservation planned for near future.

  • Pdx1 cre ( Mus musculus )

    These mice are commerically available. Cryo-preservation planned for near future.


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Last updated: 2016-03-02T19:36:21.678-05:00

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016