eagle-i University of PennsylvaniaUniversity of Pennsylvania
See it in Search

Alzheimer's Disease Genetics Consortium

Summary:

The Alzheimer's Disease Genetics Consortium is funded by a grant from the National Institute on Aging (PI, Gerard D. Schellenberg; UO1AG032984), an $18.3 million five-year research grant to conduct genome-wide association studies (GWAS) to identify genes associated with an increased risk of developing late-onset Alzheimer’s disease (LOAD).

Resources:

Databases

  • ADGC GWAS: Summary statistics for ADGC (2011) ( Database )

    "Two sets of summary statistics from Naj et al. are available: one with only p-values and one with allele frequencies and p-values. Each set of summary statistics contains six files: stage 1, stage 2, and stage 1+2 for both adjusted and unadjusted summary statistics. The p-value data is generally available to all users"

  • ADGC GWAS: Summary statistics for ADGC African Americans ( Database )

    "Genome-wide association summary statistics from an ADGC study of African Americans and their genetic risk for late-onset Alzheimer's disease is available. The files provided are both adjusted and unadjusted for APOE. The p-value data is available to all users."

  • ADGC GWAS: Summary statistics for neuropathologic features of Alzheimer's disease and related dementias ( Database )

    "A genome-wide association study and analysis of known genetic risk loci for Alzheimer's disease dementia using neuropathologic data from 4,914 brain autopsies was performed. Association analysis was performed within each cohort separately, and results were meta-analyzed across cohorts and provided here. The p-value data is generally available to all users."

Resource Collection


Web Links:

Last updated: 2016-07-13T18:31:20.921-04:00

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016