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Human inducible pluripotent stem cells- Gene Therapy Program

Summary:

Human inducible pluripotent stem cells (hiPSC) play an emerging role for individualized medicine and drug screening. The iPSC Resource Center utilizes human iPSCs in combination with directed differentiation to model genetically defined diseases, and uses this platform to screen viral vectors for gene therapy.

Affiliations:

Resources:

Services

  • hiPSC services ( Material analysis service )

    Services Performed

    1) Generation of hiPSC from somatic cells (skin fibroblast cells, PBMCs)
    2) Maintainence of hiPSC
    3) Direct differentiation of hiPSC
    -- Hepatocyte-like Cell
    -- Pancreatic β-like cell
    -- Motor Neuron
    -- Medium Spiny Neuron/GABAergic Inhibitory Neuron
    -- Dorsal Root Ganglion
    4) Genome Editing of hiPSCs
    5) Viral Vector Transduction Testing
    6) Teaching and Training on Stem Cell-Relevant Techniques
    7) High-throughput drug screening, especially for motor neurons


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Last updated: 2019-11-01T11:47:43.313-04:00

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016