The Center for Translational Lung Biology was designed to enhance lung and critical illness research by successfully integrating the clinical, translational, and basic science expertise in lung biology and critical illness, through its ability to provide the proper resources, organization, core facilities, and by supporting key recruitments. The Center is led by Dr. Jason Christie. The CTLB will work with the PCBC to provide key resources to SOM/University-wide researchers and trainees to vertically integrate basic and clinical science research through non-overlapping translational core functions focused on advanced lung diseases, lung transplantation, and critical illness syndromes. This will include a: 1) Biosample Acquisition and Clinical Data Management Core, 2) a Molecular Biology and Measurement Core, 3) a Lung Disease Modeling Core, 4) a vibrant seminar series including extramural speakers, partnered with other centers, and 5) outreach, with a focus on interacting closely with existing Departments, Centers, and Institutes to support lung disease research, especially in immunology (IFI), environmental lung diseases (CEET), epidemiology (CCEB), pediatric and neonatal lung disease (CHOP), Orphan Diseases, pulmonary vascular disease (CVI), lung transplantation (Dept. of Surgery), experimental therapies (ITMAT), and lung cancer (ACC).