The Penn Center for Musculoskeletal Disorders in the Perelman School of Medicine at the University of Pennsylvania was awarded a five-year, $4 million grant from the National Institutes of Health to continue its research on musculoskeletal injury and repair.
The Center conducts investigations in many areas of musculoskeletal biology and medicine: bones, muscles, tendons, ligaments, cartilage, and discs. The funding will support research aimed at improving the prevention, diagnosis, and treatment of conditions such as osteoporosis, osteoarthritis, low back pain, and rotator cuff tears.
Penn’s Musculoskeletal Center will provide funds for three cores of musculoskeletal research:
-- Micro–computed Tomography Imaging Core, which offers a wide range of imaging approaches to evaluate musculoskeletal tissue injury and repair. (Micro-CT is akin to three-dimensional x-ray imaging on a small scale with extremely increased resolution.)
-- Biomechanics Core, which develops and provides a large array of biomechanical approaches to evaluate musculoskeletal tissue injury and repair.
-- Histology Core, which uses and develops a wide range of approaches for the microscopic study of the structure, composition, and function of tissues and bones.
The core offers a complete spectrum of services from sample preparation and processing, to sectioning, staining and analysis, with capabilities for paraffin, plastic and frozen histology. The core provides state of the art equipment in each of these areas, which can be accessed either on a self-service basis (upon completion of training) or a full-service basis through our full-time histology technician. Service fees are highly competitive, with significant discounts offered for PCMD members.
-- Consultation and protocol development (no charge)
-- Paraffin processing and embedding
-- Paraffin sectioning
-- Plastic sectioning
-- Frozen sectioning
-- Routine histochemical staining
-- Training in histology techniques