eagle-i University of PennsylvaniaUniversity of Pennsylvania
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Arterial Hemodynamics and Cardiac Imaging Quantification Core

Director: Chirinos, Julio A., MD


We provide advanced, high-quality quantitative analysis of cardiac and arterial function for human research, particularly for mechanistic early-phase clinical trials in hypertension, heart failure, and chronic kidney disease.





  • Physical Services ( Support service )

    Site Training
    Teleconference sessions
    Assessment of Data Acquisiton Quality

  • Quantification Services ( Support service )

    Arterial tonometry
    Advanced Echocardiography Assessments
    -- Aortic input impedance
    -- Assessment of wave reflections
    -- Wave intensity analysis
    Basic and Advanced Cardiac MRI Quantification
    -- LV and RV Volumes
    -- LV and RV Strain
    -- Left and right atrial strain for advanced assessment of atrial function
    -- Extracellular volume measurements for diffuse interstitial fibrosis
    -- Standard and advanced diastolic function analyses, including modeling of intraventricular pressure gradients
    -- Aortic pulse wave velocity
    Carotid Vascular Hemodynamics to Assess Pulsatile Power Penetration into the Brain

  • Software Services ( Support service )

    Development of Custom Designed Software

  • Study Development ( Support service )

    Protocol Development and Evaluation
    Development of Site Manuals/SOPs and Case Report Forms

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Last updated: 2020-02-10T10:48:09.316-05:00

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016